Why does one infant dose (5mL) of Acetaminophen kill pain that 120mgs of oxycodone a DAY can't? I honestly would like to know. #pharmacology

Jan 19, 2017 · 8:57 AM UTC

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Replying to @mholzschlag
When I broke my left femur in two places, the doctor prescribed an oxycodone for pain. I refused. Tylenol worked fine.
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SO smart. I had past history and he was informed 21 years ago. Said "you said no opiates" I said "I'm in pain" - pad out, done.
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Opioids are symbiotic with humans, we have specific receptors for them. This allows them to "trick" our brain. @WMichelleWho
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Tylenol isn't in either class. It's actions are poorly understood. It is not directly anti-inflammatory. @WMichelleWho
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You're not far off! Anti Inflammatories: Aspirin, NSAIDs, Corticosteroids, botanicals. Opioids modify perception of pain.