Friendly, comassionate advice: "You need to do what's best for you, period." My response: "this it is not about doing what's best for me. It's about doing the most with the time I have for the most people possible how hard is that to express? Very fucking hard, apparently. :D

Profound positive impact at scale?

Or '...an exigency to impart profound positive impact at scale' Like white truffles in pasta