On a day-to-day basis, certainty in one's own beliefs is something that the scientist cannot afford; but on the scale of decades, certainty in correct contrarian beliefs is what differentiates the great careers from the rest.

May 26, 2022 · 6:08 PM UTC

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Replying to @gdb
I learned early on from the great Stanford chemist Dick Zare (via @SamuelAbramsAEI) that a good scientist has to be "a well-balanced schizophrenic"--simultaneously your own biggest fan and biggest critic. That's stuck with me because it totally applies to entrepreneurship too!
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Replying to @gdb
You can be quite certain if you have good reasons for it that most people don't know about
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